Predictive Factors Associated with the Reversibility of Post-transplantation Diabetes Mellitus Following Liver Transplantation

Post-transplantation diabetes mellitus (PTDM) is reversible in a considerable number of patients. We examined the prevalence and predictive factors of transient PTDM following liver transplantation. Forty-two of 74 PTDM patients showed the clinical features of transient PTDM. Compared with the persi...

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Detalles Bibliográficos
Autores principales: Ahn, Hwa Young, Cho, Young Min, Yi, Nam-Joon, Suh, Kyung Suk, Lee, Kuhn Uk, Park, Kyong Soo, Kim, Seong Yeon, Lee, Hong Kyu
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719195/
https://www.ncbi.nlm.nih.gov/pubmed/19654934
http://dx.doi.org/10.3346/jkms.2009.24.4.567
Descripción
Sumario:Post-transplantation diabetes mellitus (PTDM) is reversible in a considerable number of patients. We examined the prevalence and predictive factors of transient PTDM following liver transplantation. Forty-two of 74 PTDM patients showed the clinical features of transient PTDM. Compared with the persistent PTDM patients, they were characterized by younger age at the time of transplantation (49±7 vs. 53±8 yr, P<0.05), longer time before the development of PTDM (44±59 vs. 13±20 days, P<0.05), lower rate of hepatitis c virus seropositivity (0.0 vs. 9.4%, P<0.05), and use of mycophenolate mofetil (59.5 vs. 28.1%, P<0.05). Among these risk factors, age at the time of transplantation is the single independent predictive factor associated with the reversibility of PTDM.

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