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KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells
BACKGROUND: We previously described a sub-population of epithelial ovarian cancer (EOC) cells with a functional TLR-4/MyD88/NF-κB pathway (Type I EOC cells), which confers the capacity to respond to Paclitaxel, a known TLR-4 ligand, by enhancing NF-κB activity and upregulating cytokine secretion – e...
Autores principales: | Kim, Ki Hyung, Xie, Yanhua, Tytler, Ewan M, Woessner, Richard, Mor, Gil, Alvero, Ayesha B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719595/ https://www.ncbi.nlm.nih.gov/pubmed/19619321 http://dx.doi.org/10.1186/1479-5876-7-63 |
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