Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain

Activation of spinal microglia contributes to aberrant pain responses associated with neuropathic pain states. Endocannabinoids (ECs) are present in the spinal cord, and inhibit nociceptive processing; levels of ECs may be altered by microglia which modulate the turnover of endocannabinoids in vitro...

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Detalles Bibliográficos
Autores principales: Guasti, Leonardo, Richardson, Denise, Jhaveri, Maulik, Eldeeb, Khalil, Barrett, David, Elphick, Maurice R, Alexander, Stephen PH, Kendall, David, Michael, Gregory J, Chapman, Victoria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719614/
https://www.ncbi.nlm.nih.gov/pubmed/19570201
http://dx.doi.org/10.1186/1744-8069-5-35

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