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Evaluation of Tracer Kinetic Models for Analysis of [(18)F]FDDNP Studies

PURPOSE: Different pharmacokinetic methods for [(18)F]FDDNP studies were evaluated using both simulations and clinical data. PROCEDURES: Methods included two-tissue reversible plasma (2T4k), simplified reference tissue input (SRTM), and a modified 2T4k models. The latter included an additional compa...

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Detalles Bibliográficos
Autores principales: Yaqub, Maqsood, Boellaard, Ronald, van Berckel, Bart N. M., Tolboom, Nelleke, Luurtsema, Gert, Dijkstra, Anke A., Lubberink, Mark, Windhorst, Albert D., Scheltens, Philip, Lammertsma, Adriaan A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719728/
https://www.ncbi.nlm.nih.gov/pubmed/19340487
http://dx.doi.org/10.1007/s11307-009-0208-1

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