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Evaluation of Tracer Kinetic Models for Analysis of [(18)F]FDDNP Studies
PURPOSE: Different pharmacokinetic methods for [(18)F]FDDNP studies were evaluated using both simulations and clinical data. PROCEDURES: Methods included two-tissue reversible plasma (2T4k), simplified reference tissue input (SRTM), and a modified 2T4k models. The latter included an additional compa...
Autores principales: | Yaqub, Maqsood, Boellaard, Ronald, van Berckel, Bart N. M., Tolboom, Nelleke, Luurtsema, Gert, Dijkstra, Anke A., Lubberink, Mark, Windhorst, Albert D., Scheltens, Philip, Lammertsma, Adriaan A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719728/ https://www.ncbi.nlm.nih.gov/pubmed/19340487 http://dx.doi.org/10.1007/s11307-009-0208-1 |
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