Empirical correlation of triggered activity and spatial and temporal re-entrant substrates with arrhythmogenicity in a murine model for Jervell and Lange-Nielsen syndrome

KCNE1 encodes the β-subunit of the slow component of the delayed rectifier K(+) current. The Jervell and Lange-Nielsen syndrome is characterized by sensorineural deafness, prolonged QT intervals, and ventricular arrhythmogenicity. Loss-of-function mutations in KCNE1 are implicated in the JLN2 subtyp...

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Detalles Bibliográficos
Autores principales: Hothi, Sandeep S., Thomas, Glyn, Killeen, Matthew J., Grace, Andrew A., Huang, Christopher L.-H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Cardiovascular Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719739/
https://www.ncbi.nlm.nih.gov/pubmed/19430811
http://dx.doi.org/10.1007/s00424-009-0671-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719739/
https://www.ncbi.nlm.nih.gov/pubmed/19430811
http://dx.doi.org/10.1007/s00424-009-0671-1

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