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Differential Role for CD80 and CD86 in the Regulation of the Innate Immune Response in Murine Polymicrobial Sepsis

BACKGROUND: Inflammation in the early stages of sepsis is governed by the innate immune response. Costimulatory molecules are a receptor/ligand class of molecules capable of regulation of inflammation in innate immunity via macrophage/neutrophil contact. We recently described that CD80/86 ligation i...

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Detalles Bibliográficos
Autores principales:	Nolan, Anna, Kobayashi, Hiroshi, Naveed, Bushra, Kelly, Ann, Hoshino, Yoshihiko, Hoshino, Satomi, Karulf, Matthew R., Rom, William N., Weiden, Michael D., Gold, Jeffrey A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2719911/ https://www.ncbi.nlm.nih.gov/pubmed/19672303 http://dx.doi.org/10.1371/journal.pone.0006600

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