Inhibition of Akt sensitises neuroblastoma cells to gold(III) porphyrin 1a, a novel antitumour drug induced apoptosis and growth inhibition

BACKGROUND: Gold(III) porphyrin 1a is a new class of anticancer drug, which inhibits cell proliferation of wide range of human cancer cell lines and induces apoptosis in human nasopharyngeal carcinoma cells. However, the underlying signalling mechanism by which gold(III) porphyrin 1a modifies the in...

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Detalles Bibliográficos
Autores principales: Li, W, Xie, Y, Sun, R W-Y, Liu, Q, Young, J, Yu, W-Y, Che, C-M, Tam, P K, Ren, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720197/
https://www.ncbi.nlm.nih.gov/pubmed/19550420
http://dx.doi.org/10.1038/sj.bjc.6605147

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