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MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition

BACKGROUND: The X-linked inhibitor of apoptosis protein (XIAP), an endogenous apoptosis suppressor, can determine the level of caspase accumulation and the resultant response to apoptosis-inducing agents such as cisplatin in epithelial ovarian cancer (EOC). In addition, the mismatch repair protein,...

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Detalles Bibliográficos
Autores principales:	Ding, X, Mohd, A B, Huang, Z, Baba, T, Bernardini, M Q, Lyerly, H K, Berchuck, A, Murphy, S K, Buermeyer, A B, Devi, G R
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720211/ https://www.ncbi.nlm.nih.gov/pubmed/19603033 http://dx.doi.org/10.1038/sj.bjc.6605180

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