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Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array

PURPOSE: To identify new polymorphisms (single nucleotide polymorphisms, SNPs) in DNA repair pathways that are associated with efficacy and toxicity in patients receiving oxaliplatin and capecitabine for advanced colorectal cancer (ACC). METHODS: We studied progression-free survival (PFS) in 91 ACC...

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Detalles Bibliográficos
Autores principales:	Kweekel, D M, Antonini, N F, Nortier, J W R, Punt, C J A, Gelderblom, H, Guchelaar, H-J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720215/ https://www.ncbi.nlm.nih.gov/pubmed/19536092 http://dx.doi.org/10.1038/sj.bjc.6605134

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