Cargando…
MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea
BACKGROUND: Methylating agents such as N-methyl-N-nitrosourea (MNU) can cause cell cycle arrest and death either via caspase-dependent apoptosis or via a poly(ADP-ribose) polymerase (PARP)-dependent form of apoptosis. We wished to investigate the possible role of MLH1 in signalling cell death throug...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720233/ https://www.ncbi.nlm.nih.gov/pubmed/19623177 http://dx.doi.org/10.1038/sj.bjc.6605186 |
Search Result 1