Cargando…

Androgen-related expression of G-proteins in ovarian cancer

BACKGROUND: Epidemiological and in vitro data implicate androgens in the aetiology of ovarian cancer, but the mechanisms by which this is mediated are unclear. In this study, we wished to examine the effects of androgens on gene expression in ovarian cancer. METHODS: The expression of androgen recep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheach, L A, Adeney, E M, Kucukmetin, A, Wilkinson, S J, Fisher, A D, Elattar, A, Robson, C N, Edmondson, R J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2009
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720237/ https://www.ncbi.nlm.nih.gov/pubmed/19623182 http://dx.doi.org/10.1038/sj.bjc.6605153

Ejemplares similares

Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
por: Kawano, Y, et al.
Publicado: (2009)

ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival
por: Brüning-Richardson, A, et al.
Publicado: (2011)

The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer
por: de Graeff, P, et al.
Publicado: (2008)

Prognostic role of CIP2A expression in serous ovarian cancer
por: Böckelman, C, et al.
Publicado: (2011)

Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular classifiers of ovarian cancer
por: Le Page, C, et al.
Publicado: (2006)

Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling
por: Zhang, Y, et al.
Publicado: (2005)

Intracrine androgen biosynthesis in renal cell carcinoma
por: Lee, Geun Taek, et al.
Publicado: (2017)

Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cells
por: Terakawa, T, et al.
Publicado: (2009)

miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients
por: Hagman, Z, et al.
Publicado: (2013)

G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration
por: Morris, K T, et al.
Publicado: (2014)

Similar protein expression profiles of ovarian and endometrial high-grade serous carcinomas
por: Hiramatsu, Kosuke, et al.
Publicado: (2016)

Factors influencing p53 expression in ovarian cancer as a biomarker of clinical outcome in multicentre studies
por: de Graeff, P, et al.
Publicado: (2006)

Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
por: Huhtinen, K, et al.
Publicado: (2009)

CpG-island methylation study of liver fluke-related cholangiocarcinoma
por: Sriraksa, R, et al.
Publicado: (2011)

Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma
por: Arnold, J M, et al.
Publicado: (2005)

Androgen receptor phosphorylation at serine 515 by Cdk1 predicts biochemical relapse in prostate cancer patients
por: Willder, J M, et al.
Publicado: (2013)

Identification of differentially expressed genes according to chemosensitivity in advanced ovarian serous adenocarcinomas: expression of GRIA2 predicts better survival
por: Choi, C H, et al.
Publicado: (2012)

Expression of lysophosphatidic acid acyltransferase beta (LPAAT-β) in ovarian carcinoma: correlation with tumour grading and prognosis
por: Niesporek, S, et al.
Publicado: (2005)

Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer
por: Uno, K, et al.
Publicado: (2007)

MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue
por: Ghadially, Hormas, et al.
Publicado: (2017)

Androgen receptors are acquired by healthy postmenopausal endometrial epithelium and their subsequent loss in endometrial cancer is associated with poor survival
por: Kamal, A M, et al.
Publicado: (2016)

Mammaglobin B (SCGB2A1) is a novel tumour antigen highly differentially expressed in all major histological types of ovarian cancer: implications for ovarian cancer immunotherapy
por: Bellone, S, et al.
Publicado: (2013)

Enhanced expression of peroxisome proliferator-activated receptor gamma in epithelial ovarian carcinoma
por: Zhang, G Y, et al.
Publicado: (2005)

Phosphorylation of the androgen receptor is associated with reduced survival in hormone-refractory prostate cancer patients
por: McCall, P, et al.
Publicado: (2008)

Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
por: Hosono, S, et al.
Publicado: (2007)

Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer
por: Ohta, M, et al.
Publicado: (2008)

Elevated mRNA expression of CHAC1 splicing variants is associated with poor outcome for breast and ovarian cancer patients
por: Goebel, G, et al.
Publicado: (2012)

Low expression of γ-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype
por: Kawakami, K, et al.
Publicado: (2008)

Heparan sulphate synthetic and editing enzymes in ovarian cancer
por: Backen, A C, et al.
Publicado: (2007)

Minichromosome maintenance proteins 2 and 5 in non-benign epithelial ovarian tumours: relationship with cell cycle regulators and prognostic implications
por: Gakiopoulou, H, et al.
Publicado: (2007)

C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma
por: Mahner, S, et al.
Publicado: (2008)

Angiotensin II type 1 receptor expression in ovarian cancer and its correlation with tumour angiogenesis and patient survival
por: Ino, K, et al.
Publicado: (2006)

Diagnosis of prostate cancer by detection of minichromosome maintenance 5 protein in urine sediments
por: Dudderidge, T J, et al.
Publicado: (2010)

Bidirectional modulation of endogenous EpCAM expression to unravel its function in ovarian cancer
por: van der Gun, B T F, et al.
Publicado: (2013)

VEPH1 expression decreases vascularisation in ovarian cancer xenografts and inhibits VEGFA and IL8 expression through inhibition of AKT activation
por: Shathasivam, Premalatha, et al.
Publicado: (2017)

Circulating biomarkers for detection of ovarian cancer and predicting cancer outcomes
por: Shapira, I, et al.
Publicado: (2014)

Independent prognostic significance of cell cycle regulator proteins p16(INK4a) and pRb in advanced-stage ovarian carcinoma including optimally debulked patients: a translational research subprotocol of a randomised study of the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group
por: Kommoss, S, et al.
Publicado: (2007)

The human ovarian surface epithelium is an androgen responsive tissue
por: Edmondson, R J, et al.
Publicado: (2002)

Prognostic relevance of Tiam1 protein expression in prostate carcinomas
por: Engers, R, et al.
Publicado: (2006)

Whole blood-derived miRNA profiles as potential new tools for ovarian cancer screening
por: Häusler, S F M, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_o3hbfh33cggl0ftpb8bi4715c7