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A population-based cohort study on sun habits and endometrial cancer
BACKGROUND: No large cohort study has examined the risk of endometrial cancer in relation to sun exposure. METHODS: A population-based cohort study of 29 508 women who answered a questionnaire in 1990–92, of whom 24 098 responded to a follow-up enquiry in 2000–02. They were followed for an average o...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720243/ https://www.ncbi.nlm.nih.gov/pubmed/19550419 http://dx.doi.org/10.1038/sj.bjc.6605149 |
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author | Epstein, E Lindqvist, P G Geppert, B Olsson, H |
author_facet | Epstein, E Lindqvist, P G Geppert, B Olsson, H |
author_sort | Epstein, E |
collection | PubMed |
description | BACKGROUND: No large cohort study has examined the risk of endometrial cancer in relation to sun exposure. METHODS: A population-based cohort study of 29 508 women who answered a questionnaire in 1990–92, of whom 24 098 responded to a follow-up enquiry in 2000–02. They were followed for an average of 15.5 years. RESULTS: Among the 17 822 postmenopausal women included, 166 cases of endometrial cancer were diagnosed. We used a multivariate Cox regression analysis adjusting for age and other selected demographic variables to determine the risk of endometrial cancer. Women using sun beds >3 times per year reduced their hazard risk (HR) by 40% (0.6, 95% confidence interval (CI) 0.4–0.9) or by 50% when adjusting for body mass index or physical activity (HR 0.5, 95% CI 0.3–0.9), and those women who were sunbathing during summer reduced their risk by 20% (HR 0.8 95% CI 0.5–1.5) compared with women who did not expose themselves to the sun or to artificial sun (i.e., sun beds). CONCLUSION: Exposure to artificial sun by the use of sun beds >3 times per year was associated with a 40% reduction in the risk of endometrial cancer, probably by improving the vitamin D levels during winter. |
format | Text |
id | pubmed-2720243 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-27202432010-08-04 A population-based cohort study on sun habits and endometrial cancer Epstein, E Lindqvist, P G Geppert, B Olsson, H Br J Cancer Epidemiology BACKGROUND: No large cohort study has examined the risk of endometrial cancer in relation to sun exposure. METHODS: A population-based cohort study of 29 508 women who answered a questionnaire in 1990–92, of whom 24 098 responded to a follow-up enquiry in 2000–02. They were followed for an average of 15.5 years. RESULTS: Among the 17 822 postmenopausal women included, 166 cases of endometrial cancer were diagnosed. We used a multivariate Cox regression analysis adjusting for age and other selected demographic variables to determine the risk of endometrial cancer. Women using sun beds >3 times per year reduced their hazard risk (HR) by 40% (0.6, 95% confidence interval (CI) 0.4–0.9) or by 50% when adjusting for body mass index or physical activity (HR 0.5, 95% CI 0.3–0.9), and those women who were sunbathing during summer reduced their risk by 20% (HR 0.8 95% CI 0.5–1.5) compared with women who did not expose themselves to the sun or to artificial sun (i.e., sun beds). CONCLUSION: Exposure to artificial sun by the use of sun beds >3 times per year was associated with a 40% reduction in the risk of endometrial cancer, probably by improving the vitamin D levels during winter. Nature Publishing Group 2009-08-04 2009-06-23 /pmc/articles/PMC2720243/ /pubmed/19550419 http://dx.doi.org/10.1038/sj.bjc.6605149 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Epidemiology Epstein, E Lindqvist, P G Geppert, B Olsson, H A population-based cohort study on sun habits and endometrial cancer |
title | A population-based cohort study on sun habits and endometrial cancer |
title_full | A population-based cohort study on sun habits and endometrial cancer |
title_fullStr | A population-based cohort study on sun habits and endometrial cancer |
title_full_unstemmed | A population-based cohort study on sun habits and endometrial cancer |
title_short | A population-based cohort study on sun habits and endometrial cancer |
title_sort | population-based cohort study on sun habits and endometrial cancer |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720243/ https://www.ncbi.nlm.nih.gov/pubmed/19550419 http://dx.doi.org/10.1038/sj.bjc.6605149 |
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