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Computation of Conformational Coupling in Allosteric Proteins
In allosteric regulation, an effector molecule binding a protein at one site induces conformational changes, which alter structure and function at a distant active site. Two key challenges in the computational modeling of allostery are the prediction of the structure of one allosteric state starting...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720451/ https://www.ncbi.nlm.nih.gov/pubmed/19714199 http://dx.doi.org/10.1371/journal.pcbi.1000484 |