Specific gene hypomethylation and cancer: New insights into coding region feature trends

Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been pe...

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Detalles Bibliográficos
Autores principales: Daura-Oller, Elias, Cabre, Maria, Montero, Miguel A, Paternain, Jose L, Romeu, Antoni
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2009
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720671/
https://www.ncbi.nlm.nih.gov/pubmed/19707296
Descripción
Sumario:Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.

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