Specific gene hypomethylation and cancer: New insights into coding region feature trends

Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been pe...

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Detalles Bibliográficos
Autores principales: Daura-Oller, Elias, Cabre, Maria, Montero, Miguel A, Paternain, Jose L, Romeu, Antoni
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2009
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720671/
https://www.ncbi.nlm.nih.gov/pubmed/19707296
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author Daura-Oller, Elias
Cabre, Maria
Montero, Miguel A
Paternain, Jose L
Romeu, Antoni
author_facet Daura-Oller, Elias
Cabre, Maria
Montero, Miguel A
Paternain, Jose L
Romeu, Antoni
author_sort Daura-Oller, Elias
collection PubMed
description Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.
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spelling pubmed-27206712009-08-25 Specific gene hypomethylation and cancer: New insights into coding region feature trends Daura-Oller, Elias Cabre, Maria Montero, Miguel A Paternain, Jose L Romeu, Antoni Bioinformation Hypothesis Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers. Biomedical Informatics Publishing Group 2009-04-21 /pmc/articles/PMC2720671/ /pubmed/19707296 Text en © 2009 Biomedical Informatics Publishing Group This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Hypothesis
Daura-Oller, Elias
Cabre, Maria
Montero, Miguel A
Paternain, Jose L
Romeu, Antoni
Specific gene hypomethylation and cancer: New insights into coding region feature trends
title Specific gene hypomethylation and cancer: New insights into coding region feature trends
title_full Specific gene hypomethylation and cancer: New insights into coding region feature trends
title_fullStr Specific gene hypomethylation and cancer: New insights into coding region feature trends
title_full_unstemmed Specific gene hypomethylation and cancer: New insights into coding region feature trends
title_short Specific gene hypomethylation and cancer: New insights into coding region feature trends
title_sort specific gene hypomethylation and cancer: new insights into coding region feature trends
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720671/
https://www.ncbi.nlm.nih.gov/pubmed/19707296
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AT paternainjosel specificgenehypomethylationandcancernewinsightsintocodingregionfeaturetrends
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