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S16 throws a conformational switch during assembly of 30S 5′ domain

Rapid and accurate assembly of new ribosomal subunits is essential for cell growth. Here, we show that the ribosomal proteins make assembly more cooperative by discriminating against non-native conformations of the E. coli 16S rRNA. We used hydroxyl radical footprinting to measure how much the prote...

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Detalles Bibliográficos
Autores principales: Ramaswamy, Priya, Woodson, Sarah A.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720800/
https://www.ncbi.nlm.nih.gov/pubmed/19343072
http://dx.doi.org/10.1038/nsmb.1585