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Neither in vivo MRI nor behavioural assessment indicate therapeutic efficacy for a novel 5HT(1A )agonist in rat models of ischaemic stroke

BACKGROUND: 5HT(1A )agonists have previously been shown to promote recovery in animal models of stroke using ex vivo outcome measures which have raised the hopes for a potential clinical implementation. The purpose of this study was to evaluate the potential neuroprotective properties of a novel 5HT...

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Detalles Bibliográficos
Autores principales: Ashioti, Maria, Beech, John S, Lowe, Andrew S, Bernanos, Michel, McCreary, Andrew, Modo, Michel M, Williams, Steve CR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720976/
https://www.ncbi.nlm.nih.gov/pubmed/19607699
http://dx.doi.org/10.1186/1471-2202-10-82