Regulation of MYCN expression in human neuroblastoma cells

BACKGROUND: Amplification of the MYCN gene in neuroblastoma (NB) is associated with a poor prognosis. However, MYCN-amplification does not automatically result in higher expression of MYCN in children with NB. We hypothesized that the discrepancy between MYCN gene expression and prognosis in these c...

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Detalles Bibliográficos
Autores principales: Jacobs, Joannes FM, van Bokhoven, Hans, van Leeuwen, Frank N, Hulsbergen-van de Kaa, Christina A, de Vries, I Jolanda M, Adema, Gosse J, Hoogerbrugge, Peter M, de Brouwer, Arjan PM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720985/
https://www.ncbi.nlm.nih.gov/pubmed/19615087
http://dx.doi.org/10.1186/1471-2407-9-239

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