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Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it?
Connective tissue growth factor (CTGF/CCN2) is a member of the CCN family of matricellular proteins. Its expression is induced by a number of factors including TGF-β. It has been associated with fibrosis in various tissues including the kidney. Diabetic nephropathy (DN) develops in about 30% of pati...
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| Formato: | Texto |
| Lenguaje: | English |
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Springer Netherlands
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721079/ https://www.ncbi.nlm.nih.gov/pubmed/19214781 http://dx.doi.org/10.1007/s12079-009-0038-6 |