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CCN3: a key growth regulator in Chronic Myeloid Leukaemia

Chronic Myeloid Leukaemia (CML) is characterized by expression of the constitutively active Bcr-Abl tyrosine kinase. We have shown previously that the negative growth regulator, CCN3, is down-regulated as a result of Bcr-Abl kinase activity and that CCN3 has a reciprocal relationship of expression w...

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Detalles Bibliográficos
Autores principales: McCallum, Lynn, Lu, Wanhua, Price, Susan, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721087/
https://www.ncbi.nlm.nih.gov/pubmed/19623482
http://dx.doi.org/10.1007/s12079-009-0058-2