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CCN3: a key growth regulator in Chronic Myeloid Leukaemia
Chronic Myeloid Leukaemia (CML) is characterized by expression of the constitutively active Bcr-Abl tyrosine kinase. We have shown previously that the negative growth regulator, CCN3, is down-regulated as a result of Bcr-Abl kinase activity and that CCN3 has a reciprocal relationship of expression w...
Autores principales: | McCallum, Lynn, Lu, Wanhua, Price, Susan, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721087/ https://www.ncbi.nlm.nih.gov/pubmed/19623482 http://dx.doi.org/10.1007/s12079-009-0058-2 |
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