Structure-based design of anticancer prodrug PABA/NO

Glutathione S-transferase (GST) is a superfamily of detoxification enzymes, represented by GSTα, GSTμ, GSTπ, etc. GSTα is the predominant isoform of GST in human liver, playing important roles for our well being. GSTπ is overexpressed in many forms of cancer, thus presenting an opportunity for selec...

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Detalles Bibliográficos
Autores principales: Ji, Xinhua, Pal, Ajai, Kalathur, Ravi, Hu, Xun, Gu, Yijun, Saavedra, Joseph E, Buzard, Gregory S, Srinivasan, Aloka, Keefer, Larry K, Singh, Shivendra V
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721280/
https://www.ncbi.nlm.nih.gov/pubmed/19662104

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