Cargando…
The RAS/mitogen activated protein (MAP) kinase pathway in melanoma biology and therapeutics
An effective treatment for metastatic melanoma remains one of the most elusive goals in all of oncology. Several generations of therapeutic trials have yet to yield any agents that can significantly prolong survival for widespread disease. Despite this disheartening history, our understanding of the...
Autores principales: | Jarell, Abel D, Lawrence, Donald, Tsao, Hensin |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721285/ https://www.ncbi.nlm.nih.gov/pubmed/19707310 |
Ejemplares similares
-
Ras Mitogen-activated Protein Kinase Signaling and Kinase Suppressor of Ras as Therapeutic Targets for Hepatocellular Carcinoma
por: Moon, Hyuk, et al.
Publicado: (2021) -
Mapping out the mitogen activated protein kinase pathway
por: Firestein, GS
Publicado: (2004) -
Exploring the Molecular Landscape of Myelofibrosis, with a Focus on Ras and Mitogen-Activated Protein (MAP) Kinase Signaling
por: Reynolds, Samuel B., et al.
Publicado: (2023) -
KIT and Melanoma: Biological Insights and Clinical Implications
por: Pham, Duc (Daniel) M., et al.
Publicado: (2020) -
The Kinase Activity-deficient Isoform of the Protein Araf Antagonizes Ras/Mitogen-activated Protein Kinase (Ras/MAPK) Signaling in the Zebrafish Embryo
por: Xiong, Cong, et al.
Publicado: (2015)