Cetuximab in the management of colorectal cancer

Cetuximab, a chimeric IgG1 monoclonal antibody that targets the ligand-binding domain of the epidermal growth factor receptor (EGFR), is active in metastatic colorectal cancer (mCRC). As an IgG1 antibody, cetuximab may exert its antitumor efficacy through both EGFR antagonism and antibody-dependent...

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Detalles Bibliográficos
Autor principal: Lenz, Heinz-Josef
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721306/
https://www.ncbi.nlm.nih.gov/pubmed/19707318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721306/
https://www.ncbi.nlm.nih.gov/pubmed/19707318

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