Clinical activities of the epidermal growth factor receptor family inhibitors in breast cancer

The epidermal growth factor (EGF) receptors play an important role in epithelial cell function. Upon stimulation of these receptors, an extensive network of signal transduction pathways is activated, including the PI3K/AKT and Ras/Erk pathways. This activation leads to cellular proliferation and sur...

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Detalles Bibliográficos
Autores principales: Henson, Elizabeth S, Johnston, James B, Los, Marek, Gibson, Spencer B
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721308/
https://www.ncbi.nlm.nih.gov/pubmed/19707333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721308/
https://www.ncbi.nlm.nih.gov/pubmed/19707333

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