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Nonsurgical treatment of male infertility: specific and empiric therapy

Management of male infertility is always a difficult task, and the pathologic process is often poorly understood. Even though modern assisted reproduction techniques (ART) can help overcome severe male factor infertility, the application of these methods in all infertile couples would definitely rep...

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Detalles Bibliográficos
Autores principales: Cocuzza, Marcello, Agarwal, Ashok
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721319/
https://www.ncbi.nlm.nih.gov/pubmed/19707335
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author Cocuzza, Marcello
Agarwal, Ashok
author_facet Cocuzza, Marcello
Agarwal, Ashok
author_sort Cocuzza, Marcello
collection PubMed
description Management of male infertility is always a difficult task, and the pathologic process is often poorly understood. Even though modern assisted reproduction techniques (ART) can help overcome severe male factor infertility, the application of these methods in all infertile couples would definitely represent over-treatment. Several conditions can interfere with spermatogenesis and reduce sperm quality and production. A careful diagnostic work-up is necessary before any andrological treatment can be initiated so that adequate treatment options can be selected for individual patients. Most hormonal imbalances can be readily identified and successfully treated nonsurgically. However, the treatment of men with unexplained idiopathic infertility remains a challenge. In the absence of a correctable etiology, patients are managed with either empirical medical therapy or ART. Empiric medical therapy continues as a viable option. However, physicians and patients must understand that the success rates with any of the pharmacological therapies remain suboptimal.
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spelling pubmed-27213192009-08-25 Nonsurgical treatment of male infertility: specific and empiric therapy Cocuzza, Marcello Agarwal, Ashok Biologics Review Management of male infertility is always a difficult task, and the pathologic process is often poorly understood. Even though modern assisted reproduction techniques (ART) can help overcome severe male factor infertility, the application of these methods in all infertile couples would definitely represent over-treatment. Several conditions can interfere with spermatogenesis and reduce sperm quality and production. A careful diagnostic work-up is necessary before any andrological treatment can be initiated so that adequate treatment options can be selected for individual patients. Most hormonal imbalances can be readily identified and successfully treated nonsurgically. However, the treatment of men with unexplained idiopathic infertility remains a challenge. In the absence of a correctable etiology, patients are managed with either empirical medical therapy or ART. Empiric medical therapy continues as a viable option. However, physicians and patients must understand that the success rates with any of the pharmacological therapies remain suboptimal. Dove Medical Press 2007-09 2007-09 /pmc/articles/PMC2721319/ /pubmed/19707335 Text en © 2007 Dove Medical Press Limited. All rights reserved
spellingShingle Review
Cocuzza, Marcello
Agarwal, Ashok
Nonsurgical treatment of male infertility: specific and empiric therapy
title Nonsurgical treatment of male infertility: specific and empiric therapy
title_full Nonsurgical treatment of male infertility: specific and empiric therapy
title_fullStr Nonsurgical treatment of male infertility: specific and empiric therapy
title_full_unstemmed Nonsurgical treatment of male infertility: specific and empiric therapy
title_short Nonsurgical treatment of male infertility: specific and empiric therapy
title_sort nonsurgical treatment of male infertility: specific and empiric therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721319/
https://www.ncbi.nlm.nih.gov/pubmed/19707335
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