Infliximab in ulcerative colitis

Infliximab, a monoclonal anti-TNF-α antibody, is commonly used for treatment of moderate to severe Crohn’s disease (CD). Its role in the treatment for ulcerative colitis (UC) remains controversial. We review the role of TNF-α in the pathogenesis of UC and describe the randomized, double-blind, place...

Descripción completa

Detalles Bibliográficos
Autores principales: Levin, Avi, Shibolet, Oren
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721383/
https://www.ncbi.nlm.nih.gov/pubmed/19707369
_version_ 1782170191551004672
author Levin, Avi
Shibolet, Oren
author_facet Levin, Avi
Shibolet, Oren
author_sort Levin, Avi
collection PubMed
description Infliximab, a monoclonal anti-TNF-α antibody, is commonly used for treatment of moderate to severe Crohn’s disease (CD). Its role in the treatment for ulcerative colitis (UC) remains controversial. We review the role of TNF-α in the pathogenesis of UC and describe the randomized, double-blind, placebo-controlled trials and systematic reviews that assess the efficacy of infliximab in the treatment of moderate to severe UC.
format Text
id pubmed-2721383
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-27213832009-08-25 Infliximab in ulcerative colitis Levin, Avi Shibolet, Oren Biologics Review Infliximab, a monoclonal anti-TNF-α antibody, is commonly used for treatment of moderate to severe Crohn’s disease (CD). Its role in the treatment for ulcerative colitis (UC) remains controversial. We review the role of TNF-α in the pathogenesis of UC and describe the randomized, double-blind, placebo-controlled trials and systematic reviews that assess the efficacy of infliximab in the treatment of moderate to severe UC. Dove Medical Press 2008-09 2008-09 /pmc/articles/PMC2721383/ /pubmed/19707369 Text en © 2008 Dove Medical Press Limited. All rights reserved
spellingShingle Review
Levin, Avi
Shibolet, Oren
Infliximab in ulcerative colitis
title Infliximab in ulcerative colitis
title_full Infliximab in ulcerative colitis
title_fullStr Infliximab in ulcerative colitis
title_full_unstemmed Infliximab in ulcerative colitis
title_short Infliximab in ulcerative colitis
title_sort infliximab in ulcerative colitis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721383/
https://www.ncbi.nlm.nih.gov/pubmed/19707369
work_keys_str_mv AT levinavi infliximabinulcerativecolitis
AT shiboletoren infliximabinulcerativecolitis

Ejemplares similares