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Deregulation of Hepatic Insulin Sensitivity Induced by Central Lipid Infusion in Rats Is Mediated by Nitric Oxide
BACKGROUND: Deregulation of hypothalamic fatty acid sensing lead to hepatic insulin-resistance which may partly contribute to further impairment of glucose homeostasis. METHODOLOGY: We investigated here whether hypothalamic nitric oxide (NO) could mediate deleterious peripheral effect of central lip...
Autores principales: | Marsollier, Nicolas, Kassis, Nadim, Mezghenna, Karima, Soty, Maud, Fioramonti, Xavier, Lacombe, Amélie, Joly, Aurélie, Pillot, Bruno, Zitoun, Carine, Vilar, José, Mithieux, Gilles, Gross, René, Lajoix, Anne-Dominique, Routh, Vanessa, Magnan, Christophe, Cruciani-Guglielmacci, Céline |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721417/ https://www.ncbi.nlm.nih.gov/pubmed/19680547 http://dx.doi.org/10.1371/journal.pone.0006649 |
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