Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors

As a continued effort to develop multivalent ligands to enhance the pharmacological effects of monomeric drugs, DITC-APEC, a chemically reactive nucleoside A(2A) adenosine receptor (AR) agonist, was employed to derivatize the surface of third-generation (G3) polyamidoamine (PAMAM) dendrimers. The re...

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Detalles Bibliográficos
Autores principales: Kim, Yoonkyung, Klutz, Athena M., Hechler, Béatrice, Gao, Zhan-Guo, Gachet, Christian, Jacobson, Kenneth A.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721767/
https://www.ncbi.nlm.nih.gov/pubmed/18600474
http://dx.doi.org/10.1007/s11302-008-9113-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721767/
https://www.ncbi.nlm.nih.gov/pubmed/18600474
http://dx.doi.org/10.1007/s11302-008-9113-3

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