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Selective P2X(7) receptor antagonists for chronic inflammation and pain

ATP, acting on P2X(7) receptors, stimulates changes in intracellular calcium concentrations, maturation, and release of interleukin-1β (IL-1β), and following prolonged agonist exposure, cell death. The functional effects of P2X(7) receptor activation facilitate several proinflammatory processes asso...

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Detalles Bibliográficos
Autores principales:	Carroll, William A., Donnelly-Roberts, Diana, Jarvis, Michael F.
Formato:	Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2008
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721772/ https://www.ncbi.nlm.nih.gov/pubmed/18568426 http://dx.doi.org/10.1007/s11302-008-9110-6

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