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Chronic Dietary Exposure to a Low-Dose Mixture of Genistein and Vinclozolin Modifies the Reproductive Axis, Testis Transcriptome, and Fertility

BACKGROUND: The reproductive consequences and mechanisms of action of chronic exposure to low-dose endocrine disruptors are poorly understood. OBJECTIVE: We assessed the effects of a continuous, low-dose exposure to a phytoestrogen (genistein) and/or an antiandrogenic food contaminant (vinclozolin)...

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Detalles Bibliográficos
Autores principales: Eustache, Florence, Mondon, Françoise, Canivenc-Lavier, Marie Chantal, Lesaffre, Corinne, Fulla, Yvonne, Berges, Raymond, Cravedi, Jean Pierre, Vaiman, Daniel, Auger, Jacques
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721872/
https://www.ncbi.nlm.nih.gov/pubmed/19672408
http://dx.doi.org/10.1289/ehp.0800158