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Multiple functions of MRN in end-joining pathways during isotype class switching

The Mre11/Rad50/NBS1 (MRN) complex plays many roles in response to DNA double strand breaks (DSBs), but its functions in repair by non homologous end joining (NHEJ) pathways are poorly understood. We have investigated requirements for MRN in Class Switch Recombination (CSR), a programmed DNA rearran...

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Detalles Bibliográficos
Autores principales:	Dinkelmann, Maria, Spehalski, Elizabeth, Stoneham, Trina, Buis, Jeffrey, Wu, Yipin, Sekiguchi, JoAnn M., Ferguson, David O.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721910/ https://www.ncbi.nlm.nih.gov/pubmed/19633670 http://dx.doi.org/10.1038/nsmb.1639

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