IL-2 Pathway Blocking in Combination with Anti-CD154 Synergistically Establishes Mixed Macrochimerism with Limited Dose of Bone Marrow Cells and Prolongs Skin Graft Survival in Mice

To facilitate the establishment of mixed chimerism with limited dose of bone marrow (BM) cells, and to achieve tolerance in skin graft model, combined blocking of costimulatory pathway and IL-2 pathway was used in minimally myeloablative model using busulfan. BM cells (2.5×10(7)) of BALB/c were inje...

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Detalles Bibliográficos
Autores principales: Lee, Jeong-hoon, Ha, Jongwon, Kim, Shi-hwa, Kim, Sang Joon
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2006
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721919/
https://www.ncbi.nlm.nih.gov/pubmed/17179677
http://dx.doi.org/10.3346/jkms.2006.21.6.1005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721919/
https://www.ncbi.nlm.nih.gov/pubmed/17179677
http://dx.doi.org/10.3346/jkms.2006.21.6.1005

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