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Loss of Anti-Bax Function in Gerstmann-Sträussler-Scheinker Syndrome-Associated Prion Protein Mutants

Previously, we have shown the loss of anti-Bax function in Creutzfeldt Jakob disease (CJD)-associated prion protein (PrP) mutants that are unable to generate cytosolic PrP (CyPrP). To determine if the anti-Bax function of PrP modulates the manifestation of prion diseases, we further investigated the...

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Detalles Bibliográficos
Autores principales:	Jodoin, Julie, Misiewicz, Micheal, Makhijani, Priya, Giannopoulos, Paresa N., Hammond, Jennifer, Goodyer, Cynthia G., LeBlanc, Andréa C.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722024/ https://www.ncbi.nlm.nih.gov/pubmed/19680558 http://dx.doi.org/10.1371/journal.pone.0006647

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