Cargando…

Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen

Variable lymphocyte receptors (VLRs) are leucine-rich repeat (LRR) proteins that mediate adaptive immunity in jawless vertebrates. VLRs are fundamentally different from the antibodies of jawed vertebrates, which consist of immunoglobulin (Ig) domains. We determined the structure of an anti-hen egg w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Velikovsky, C Alejandro, Deng, Lu, Tasumi, Satoshi, Iyer, Lakshminarayan M, Kerzic, Melissa C, Aravind, L, Pancer, Zeev, Mariuzza, Roy A
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722044/ https://www.ncbi.nlm.nih.gov/pubmed/19543291 http://dx.doi.org/10.1038/nsmb.1619

Ejemplares similares

Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors
por: Moot, Robert, et al.
Publicado: (2016)

Identification of lamprey variable lymphocyte receptors that target the brain vasculature
por: Lajoie, Jason M., et al.
Publicado: (2022)

Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification
por: Iyer, Lakshminarayan M., et al.
Publicado: (2015)

Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys
por: Holland, Stephen J., et al.
Publicado: (2018)

Crystal Structure of the Lamprey Variable Lymphocyte Receptor C Reveals an Unusual Feature in Its N-Terminal Capping Module
por: Kanda, Ryo, et al.
Publicado: (2014)

Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA
por: Iyer, Lakshminarayan M., et al.
Publicado: (2013)

The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities
por: Aravind, L, et al.
Publicado: (2002)

The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates
por: Iyer, Lakshminarayan M, et al.
Publicado: (2002)

ALOG domains: provenance of plant homeotic and developmental regulators from the DNA-binding domain of a novel class of DIRS1-type retroposons
por: Iyer, Lakshminarayan M, et al.
Publicado: (2012)

The Cell Wall Lipid PDIM Contributes to Phagosomal Escape and Host Cell Exit of Mycobacterium tuberculosis
por: Quigley, Jeff, et al.
Publicado: (2017)

HPC2 and ubinuclein define a novel family of histone chaperones conserved throughout eukaryotes
por: Balaji, S., et al.
Publicado: (2009)

Detection and Neutralization of SARS-CoV-2 Using Non-conventional Variable Lymphocyte Receptor Antibodies of the Evolutionarily Distant Sea Lamprey
por: Leung, Leslie Y. T., et al.
Publicado: (2021)

Lamprey VLRB response to influenza virus supports universal rules of immunogenicity and antigenicity
por: Altman, Meghan O, et al.
Publicado: (2015)

Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells
por: Urbanowicz, Richard A., et al.
Publicado: (2019)

MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases
por: Iyer, Lakshminarayan M, et al.
Publicado: (2008)

Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitination
por: Iyer, Lakshminarayan M, et al.
Publicado: (2008)

A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases
por: Iyer, Lakshminarayan M, et al.
Publicado: (2008)

The two faces of Alba: the evolutionary connection between proteins participating in chromatin structure and RNA metabolism
por: Aravind, L, et al.
Publicado: (2003)

A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems
por: Zhang, Dapeng, et al.
Publicado: (2011)

Presence of a classical RRM-fold palm domain in Thg1-type 3'- 5'nucleic acid polymerases and the origin of the GGDEF and CRISPR polymerase domains
por: Anantharaman, Vivek, et al.
Publicado: (2010)

Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins
por: Iyer, Lakshminarayan M, et al.
Publicado: (2003)

Novel autoproteolytic and DNA-damage sensing components in the bacterial SOS response and oxidized methylcytosine-induced eukaryotic DNA demethylation systems
por: Aravind, L, et al.
Publicado: (2013)

THE NATURE OF THE LAMPREY VISUAL PIGMENT
por: Crescitelli, Frederick
Publicado: (1956)

The rise of predation in Jurassic lampreys
por: Wu, Feixiang, et al.
Publicado: (2023)

Lamprey (Entosphenus sp. and Lampetra sp.) estuarine occupancy is regionally variable and constrained by temperature
por: Goertler, Pascale A. L., et al.
Publicado: (2019)

The sea lamprey meiotic map improves resolution of ancient vertebrate genome duplications
por: Smith, Jeramiah J., et al.
Publicado: (2015)

The prokaryotic antecedents of the ubiquitin-signaling system and the early evolution of ubiquitin-like β-grasp domains
por: Iyer, Lakshminarayan M, et al.
Publicado: (2006)

Classification and evolutionary history of the single-strand annealing proteins, RecT, Redβ, ERF and RAD52
por: Iyer, Lakshminarayan M, et al.
Publicado: (2002)

Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases
por: Iyer, Lakshminarayan M, et al.
Publicado: (2003)

Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES transcription factors
por: Iyer, Lakshminarayan M, et al.
Publicado: (2002)

Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes
por: Burroughs, A Maxwell, et al.
Publicado: (2013)

THE METAMORPHOSIS OF VISUAL SYSTEMS IN THE SEA LAMPREY
por: Wald, George
Publicado: (1957)

THE HEMOGLOBIN OF THE SEA LAMPREY, PETROMYZON MARINUS
por: Wald, George, et al.
Publicado: (1951)

An inhibitory receptor of VLRB in the agnathan lamprey
por: Wu, Fenfang, et al.
Publicado: (2016)

GABAergic modulation of olfactomotor transmission in lampreys
por: Daghfous, Gheylen, et al.
Publicado: (2018)

A novel superfamily containing the β-grasp fold involved in binding diverse soluble ligands
por: Burroughs, A Maxwell, et al.
Publicado: (2007)

The natural history of the WRKY–GCM1 zinc fingers and the relationship between transcription factors and transposons
por: Babu, M. Madan, et al.
Publicado: (2006)

Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains
por: Balaji, S., et al.
Publicado: (2005)

Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold
por: Burroughs, A Maxwell, et al.
Publicado: (2007)

Identification of the prokaryotic ligand-gated ion channels and their implications for the mechanisms and origins of animal Cys-loop ion channels
por: Tasneem, Asba, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_u2mmm12bvp0r6afuknj6m5ebjo