Cargando…
Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently...
Autores principales: | Carlin, Aaron F., Chang, Yung-Chi, Areschoug, Thomas, Lindahl, Gunnar, Hurtado-Ziola, Nancy, King, Charles C., Varki, Ajit, Nizet, Victor |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722167/ https://www.ncbi.nlm.nih.gov/pubmed/19596804 http://dx.doi.org/10.1084/jem.20090691 |
Ejemplares similares
-
Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus
por: Ali, Syed Raza, et al.
Publicado: (2014) -
Group B Streptococcus Engages an Inhibitory Siglec through Sialic Acid Mimicry to Blunt Innate Immune and Inflammatory Responses In Vivo
por: Chang, Yung-Chi, et al.
Publicado: (2014) -
Human Siglec-5 Inhibitory Receptor and Immunoglobulin A (IgA) Have Separate Binding Sites in Streptococcal β Protein
por: Nordström, Therése, et al.
Publicado: (2011) -
Tamm-Horsfall glycoprotein engages human Siglec-9 to modulate neutrophil activation in the urinary tract
por: Patras, Kathryn A., et al.
Publicado: (2017) -
Evolution of the exclusively human pathogen Neisseria gonorrhoeae: Human‐specific engagement of immunoregulatory Siglecs
por: Landig, Corinna S., et al.
Publicado: (2019)