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Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia

Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patien...

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Autores principales: Oikawa, Tetsuro, Ito, Go, Hoshino, Takayuki, Koyama, Hidehiko, Hanawa, Toshihiko
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722198/
https://www.ncbi.nlm.nih.gov/pubmed/18955239
http://dx.doi.org/10.1093/ecam/nem101
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author Oikawa, Tetsuro
Ito, Go
Hoshino, Takayuki
Koyama, Hidehiko
Hanawa, Toshihiko
author_facet Oikawa, Tetsuro
Ito, Go
Hoshino, Takayuki
Koyama, Hidehiko
Hanawa, Toshihiko
author_sort Oikawa, Tetsuro
collection PubMed
description Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patients with FD from the standpoint of bowel gas retention. The bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients was significantly higher than that in healthy subjects. Two week administration of HKT in the FD patients showed a significant decrease of GVS. Furthermore, gastrointestinal symptoms, especially symptoms of abdominal pain, indigestion and constipation, all of which are closely related to abdominal bloating, improved significantly in FD patients after the administration of HKT. These results suggest that HKT improves abdominal bloating accompanied by the reduction of bowel gas in FD patients.
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spelling pubmed-27221982009-08-06 Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia Oikawa, Tetsuro Ito, Go Hoshino, Takayuki Koyama, Hidehiko Hanawa, Toshihiko Evid Based Complement Alternat Med Original Articles - Clinical Analyses Although abdominal bloating is one of the most bothersome symptoms experienced by patients with functional dyspepsia (FD), therapeutic drugs to relieve abdominal bloating have not been established. We investigated the Kampo (Chinese herbal) medicine, Hangekobokuto (Banxia-houpo-tang, HKT) for patients with FD from the standpoint of bowel gas retention. The bowel gas volume calculated from a plain abdominal radiogram (gas volume score, GVS) in FD patients was significantly higher than that in healthy subjects. Two week administration of HKT in the FD patients showed a significant decrease of GVS. Furthermore, gastrointestinal symptoms, especially symptoms of abdominal pain, indigestion and constipation, all of which are closely related to abdominal bloating, improved significantly in FD patients after the administration of HKT. These results suggest that HKT improves abdominal bloating accompanied by the reduction of bowel gas in FD patients. Oxford University Press 2009-09 2007-10-04 /pmc/articles/PMC2722198/ /pubmed/18955239 http://dx.doi.org/10.1093/ecam/nem101 Text en © 2007 The Author(s). http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles - Clinical Analyses
Oikawa, Tetsuro
Ito, Go
Hoshino, Takayuki
Koyama, Hidehiko
Hanawa, Toshihiko
Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_full Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_fullStr Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_full_unstemmed Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_short Hangekobokuto (Banxia-houpo-tang), a Kampo Medicine that Treats Functional Dyspepsia
title_sort hangekobokuto (banxia-houpo-tang), a kampo medicine that treats functional dyspepsia
topic Original Articles - Clinical Analyses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722198/
https://www.ncbi.nlm.nih.gov/pubmed/18955239
http://dx.doi.org/10.1093/ecam/nem101
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