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Telomeres and disease

The telomeres of most eukaryotes are characterized by guanine-rich repeats synthesized by the reverse transcriptase telomerase. Complete loss of telomerase is tolerated for several generations in most species, but modestly reduced telomerase levels in human beings are implicated in bone marrow failu...

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Detalles Bibliográficos
Autor principal: Lansdorp, Peter M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722246/
https://www.ncbi.nlm.nih.gov/pubmed/19629041
http://dx.doi.org/10.1038/emboj.2009.172