Cargando…
Telomeres and disease
The telomeres of most eukaryotes are characterized by guanine-rich repeats synthesized by the reverse transcriptase telomerase. Complete loss of telomerase is tolerated for several generations in most species, but modestly reduced telomerase levels in human beings are implicated in bone marrow failu...
Autor principal: | Lansdorp, Peter M |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722246/ https://www.ncbi.nlm.nih.gov/pubmed/19629041 http://dx.doi.org/10.1038/emboj.2009.172 |
Ejemplares similares
-
A ‘higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs
por: Schoeftner, Stefan, et al.
Publicado: (2009) -
TERRA: telomeric repeat-containing RNA
por: Luke, Brian, et al.
Publicado: (2009) -
Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase
por: Shore, David, et al.
Publicado: (2009) -
Telomere Length Regulation
por: Lansdorp, Peter
Publicado: (2022) -
Sex differences in telomere length, lifespan, and embryonic dyskerin levels
por: Lansdorp, Peter M.
Publicado: (2022)