Hexameric assembly of the proteasomal ATPases is templated through their C-termini

Substrates of the proteasome are recognized and unfolded by the regulatory particle (RP), then translocated into the core particle (CP) to be degraded1. A hetero-hexameric ATPase ring, containing subunits Rpt1-Rpt6, is situated within the base subassembly of the RP1. The ATPase ring sits atop the CP...

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Detalles Bibliográficos
Autores principales: Park, Soyeon, Roelofs, Jeroen, Kim, Woong, Robert, Jessica, Schmidt, Marion, Gygi, Steven P., Finley, Daniel
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722381/
https://www.ncbi.nlm.nih.gov/pubmed/19412160
http://dx.doi.org/10.1038/nature08065

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