An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

To address the biological heterogeneity of lung cancer, we studied 199 lung adenocarcinomas by integrating genome-wide data on copy number alterations and gene expression with full annotation for major known somatic mutations in this cancer. This revealed non-random patterns of copy number alteratio...

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Detalles Bibliográficos
Autores principales: Chitale, Dhananjay, Gong, Yixuan, Taylor, Barry S., Broderick, Stephen, Brennan, Cameron, Somwar, Romel, Golas, Benjamin, Wang, Lu, Motoi, Noriko, Szoke, Janos, Reinersman, J. Matthew, Major, John, Sander, Chris, Seshan, Venkatraman E., Zakowski, Maureen F., Rusch, Valerie, Pao, William, Gerald, William, Ladanyi, Marc
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722688/
https://www.ncbi.nlm.nih.gov/pubmed/19525976
http://dx.doi.org/10.1038/onc.2009.135

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