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The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium
Cardiac sodium channels are responsible for conduction in the normal and diseased heart. We aimed to investigate regional and transmural distribution of sodium channel expression and function in the myocardium. Sodium channel Scn5a mRNA and Na(v)1.5 protein distribution was investigated in adult and...
Autores principales: | Remme, C. A., Verkerk, A. O., Hoogaars, W. M. H., Aanhaanen, W. T. J., Scicluna, B. P., Annink, C., van den Hoff, M. J. B., Wilde, A. A. M., van Veen, T. A. B., Veldkamp, M. W., de Bakker, J. M. T., Christoffels, V. M., Bezzina, C. R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
D. Steinkopff-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722719/ https://www.ncbi.nlm.nih.gov/pubmed/19255801 http://dx.doi.org/10.1007/s00395-009-0012-8 |
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