pH Modulation of Efflux Pump Activity of Multi-Drug Resistant Escherichia coli: Protection During Its Passage and Eventual Colonization of the Colon

BACKGROUND: Resistance Nodulation Division (RND) efflux pumps of Escherichia coli extrude antibiotics and toxic substances before they reach their intended targets. Whereas these pumps obtain their energy directly from the proton motive force (PMF), ATP-Binding Cassette (ABC) transporters, which can...

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Detalles Bibliográficos
Autores principales: Martins, Ana, Spengler, Gabriella, Rodrigues, Liliana, Viveiros, Miguel, Ramos, Jorge, Martins, Marta, Couto, Isabel, Fanning, Séamus, Pagès, Jean-Marie, Bolla, Jean Michel, Molnar, Joseph, Amaral, Leonard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722724/
https://www.ncbi.nlm.nih.gov/pubmed/19684858
http://dx.doi.org/10.1371/journal.pone.0006656

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