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Systems-wide Analysis of a Phosphatase Knock-down by Quantitative Proteomics and Phosphoproteomics

Signal transduction in metazoans regulates almost all aspects of biological function, and aberrant signaling is involved in many diseases. Perturbations in phosphorylation-based signaling networks are typically studied in a hypothesis-driven approach, using phospho-specific antibodies. Here we apply...

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Detalles Bibliográficos
Autores principales:	Hilger, Maximiliane, Bonaldi, Tiziana, Gnad, Florian, Mann, Matthias
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2009
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722773/ https://www.ncbi.nlm.nih.gov/pubmed/19429919 http://dx.doi.org/10.1074/mcp.M800559-MCP200

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