Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs

Fragile X mental retardation is caused by loss-of-function of a single gene encoding FMRP, an RNA-binding protein that harbors three canonical RNA-binding domains, two KH-type and one RGG box. Two autosomal paralogs of FMRP, FXR1P and FXR2P, are similar to FMRP in their overall structure, including...

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Detalles Bibliográficos
Autores principales: Darnell, Jennifer C., Fraser, Claire E., Mostovetsky, Olga, Darnell, Robert B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722981/
https://www.ncbi.nlm.nih.gov/pubmed/19487368
http://dx.doi.org/10.1093/hmg/ddp255

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