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14-3-3σ gene silencing during melanoma progression and its role in cell cycle control and cellular senescence

BACKGROUND: The family of 14-3-3 proteins plays an important role in cancer biology by interfering with intracellular signalling pathways and cell cycle checkpoints. The 14-3-3σ isoform acts as a tumor suppressor and is often inactivated during tumor development. RESULTS: Here, we demonstrate enhanc...

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Detalles Bibliográficos
Autores principales: Schultz, Julia, Ibrahim, Saleh M, Vera, Julio, Kunz, Manfred
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723074/
https://www.ncbi.nlm.nih.gov/pubmed/19642975
http://dx.doi.org/10.1186/1476-4598-8-53