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14-3-3σ gene silencing during melanoma progression and its role in cell cycle control and cellular senescence
BACKGROUND: The family of 14-3-3 proteins plays an important role in cancer biology by interfering with intracellular signalling pathways and cell cycle checkpoints. The 14-3-3σ isoform acts as a tumor suppressor and is often inactivated during tumor development. RESULTS: Here, we demonstrate enhanc...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723074/ https://www.ncbi.nlm.nih.gov/pubmed/19642975 http://dx.doi.org/10.1186/1476-4598-8-53 |