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Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function

BACKGROUND: In this study, investigating the effects of mobile phone radiation on test animals, eleven pigs were anaesthetised to the level where burst-suppression pattern appears in the electroencephalogram (EEG). At this level of anaesthesia both human subjects and animals show high sensitivity to...

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Autores principales: Lipping, Tarmo, Rorarius, Michael, Jäntti, Ville, Annala, Kari, Mennander, Ari, Ferenets, Rain, Toivonen, Tommi, Toivo, Tim, Värri, Alpo, Korpinen, Leena
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723106/
https://www.ncbi.nlm.nih.gov/pubmed/19615084
http://dx.doi.org/10.1186/1753-4631-3-5
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author Lipping, Tarmo
Rorarius, Michael
Jäntti, Ville
Annala, Kari
Mennander, Ari
Ferenets, Rain
Toivonen, Tommi
Toivo, Tim
Värri, Alpo
Korpinen, Leena
author_facet Lipping, Tarmo
Rorarius, Michael
Jäntti, Ville
Annala, Kari
Mennander, Ari
Ferenets, Rain
Toivonen, Tommi
Toivo, Tim
Värri, Alpo
Korpinen, Leena
author_sort Lipping, Tarmo
collection PubMed
description BACKGROUND: In this study, investigating the effects of mobile phone radiation on test animals, eleven pigs were anaesthetised to the level where burst-suppression pattern appears in the electroencephalogram (EEG). At this level of anaesthesia both human subjects and animals show high sensitivity to external stimuli which produce EEG bursts during suppression. The burst-suppression phenomenon represents a nonlinear control system, where low-amplitude EEG abruptly switches to very high amplitude bursts. This switching can be triggered by very minor stimuli and the phenomenon has been described as hypersensitivity. To test if also radio frequency (RF) stimulation can trigger this nonlinear control, the animals were exposed to pulse modulated signal of a GSM mobile phone at 890 MHz. In the first phase of the experiment electromagnetic field (EMF) stimulation was randomly switched on and off and the relation between EEG bursts and EMF stimulation onsets and endpoints were studied. In the second phase a continuous RF stimulation at 31 W/kg was applied for 10 minutes. The ECG, the EEG, and the subcutaneous temperature were recorded. RESULTS: No correlation between the exposure and the EEG burst occurrences was observed in phase I measurements. No significant changes were observed in the EEG activity of the pigs during phase II measurements although several EEG signal analysis methods were applied. The temperature measured subcutaneously from the pigs' head increased by 1.6°C and the heart rate by 14.2 bpm on the average during the 10 min exposure periods. CONCLUSION: The hypothesis that RF radiation would produce sensory stimulation of somatosensory, auditory or visual system or directly affect the brain so as to produce EEG bursts during suppression was not confirmed.
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spelling pubmed-27231062009-08-08 Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function Lipping, Tarmo Rorarius, Michael Jäntti, Ville Annala, Kari Mennander, Ari Ferenets, Rain Toivonen, Tommi Toivo, Tim Värri, Alpo Korpinen, Leena Nonlinear Biomed Phys Research BACKGROUND: In this study, investigating the effects of mobile phone radiation on test animals, eleven pigs were anaesthetised to the level where burst-suppression pattern appears in the electroencephalogram (EEG). At this level of anaesthesia both human subjects and animals show high sensitivity to external stimuli which produce EEG bursts during suppression. The burst-suppression phenomenon represents a nonlinear control system, where low-amplitude EEG abruptly switches to very high amplitude bursts. This switching can be triggered by very minor stimuli and the phenomenon has been described as hypersensitivity. To test if also radio frequency (RF) stimulation can trigger this nonlinear control, the animals were exposed to pulse modulated signal of a GSM mobile phone at 890 MHz. In the first phase of the experiment electromagnetic field (EMF) stimulation was randomly switched on and off and the relation between EEG bursts and EMF stimulation onsets and endpoints were studied. In the second phase a continuous RF stimulation at 31 W/kg was applied for 10 minutes. The ECG, the EEG, and the subcutaneous temperature were recorded. RESULTS: No correlation between the exposure and the EEG burst occurrences was observed in phase I measurements. No significant changes were observed in the EEG activity of the pigs during phase II measurements although several EEG signal analysis methods were applied. The temperature measured subcutaneously from the pigs' head increased by 1.6°C and the heart rate by 14.2 bpm on the average during the 10 min exposure periods. CONCLUSION: The hypothesis that RF radiation would produce sensory stimulation of somatosensory, auditory or visual system or directly affect the brain so as to produce EEG bursts during suppression was not confirmed. BioMed Central 2009-07-18 /pmc/articles/PMC2723106/ /pubmed/19615084 http://dx.doi.org/10.1186/1753-4631-3-5 Text en Copyright © 2009 Lipping et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Lipping, Tarmo
Rorarius, Michael
Jäntti, Ville
Annala, Kari
Mennander, Ari
Ferenets, Rain
Toivonen, Tommi
Toivo, Tim
Värri, Alpo
Korpinen, Leena
Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function
title Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function
title_full Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function
title_fullStr Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function
title_full_unstemmed Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function
title_short Using the nonlinear control of anaesthesia-induced hypersensitivity of EEG at burst suppression level to test the effects of radiofrequency radiation on brain function
title_sort using the nonlinear control of anaesthesia-induced hypersensitivity of eeg at burst suppression level to test the effects of radiofrequency radiation on brain function
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723106/
https://www.ncbi.nlm.nih.gov/pubmed/19615084
http://dx.doi.org/10.1186/1753-4631-3-5
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