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Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer
BACKGROUND: There is evidence that the immune systems of patients with breast cancer are dysfunctional. Regulatory T cells (Tregs), and IDO, an immunosuppressive enzyme, are associated with more advanced disease in some cancers and may promote immunologic tolerance to tumors. Our aim was to assess w...
Autores principales: | Mansfield, Aaron S, Heikkila, Paivi S, Vaara, Ari T, von Smitten, Karl AJ, Vakkila, Jukka M, Leidenius, Marjut HK |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723126/ https://www.ncbi.nlm.nih.gov/pubmed/19604349 http://dx.doi.org/10.1186/1471-2407-9-231 |
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