Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD

BACKGROUND: It is well known that the pattern of linkage disequilibrium varies between human populations, with remarkable geographical stratification. Indirect association studies routinely exploit linkage disequilibrium around genes, particularly in isolated populations where it is assumed to be hi...

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Detalles Bibliográficos
Autores principales: Bosch, Elena, Laayouni, Hafid, Morcillo-Suarez, Carlos, Casals, Ferran, Moreno-Estrada, Andrés, Ferrer-Admetlla, Anna, Gardner, Michelle, Rosa, Araceli, Navarro, Arcadi, Comas, David, Graffelman, Jan, Calafell, Francesc, Bertranpetit, Jaume
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723139/
https://www.ncbi.nlm.nih.gov/pubmed/19638193
http://dx.doi.org/10.1186/1471-2164-10-338

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